|
|
(7R,8S)-diaminononanoate + CO2 + ATP <=> dethiobiotin + phosphate + ADP + H+
|
6.3.3.3
dethiobiotin synthase
|
–
|
BMK
|
| |
BRENDA:
BR128
KEGG:
R03182
MetaCyc:
DETHIOBIOTIN-SYN-RXN
SABIO-RK:
3011
|
|
|
|
dethiobiotin + sulfur-(sulfur_carrier) + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center <=> biotin + (sulfur_carrier) + 2 L-methionine + 2 5''-deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.6
biotin synthase
|
–
|
|
| |
BRENDA:
BR48103
SABIO-RK:
13730
|
|
|
|
dethiobiotin + Sulfur_donor + 2 S-adenosyl-L-methionine + 2 e- + 2 H+ <=> biotin + 2 L-methionine + 2 5''-Deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
K
|
| |
KEGG:
R01078
|
|
|
|
S-adenosyl-L-methionine + sulfurated_[sulfur_carrier] + dethiobiotin + [2Fe-2S]-center <=> unsulfurated_[sulfur_carrier] + biotin + 5''-deoxyadenosine + L-methionine + [2Fe-2S]-center
|
2.8.1.6
biotin synthase
|
–
|
|
| |
MetaCyc:
2.8.1.6-RXN
|
|
|
|
S-adenosyl-L-methionine + sulfurated_[sulfur_carrier] + dethiobiotin + [2Fe-2S]-center + H+ <=> unsulfurated_[sulfur_carrier] + 9-Mercaptodethiobiotin + 5''-deoxyadenosine + L-methionine + [2Fe-2S]-center
|
not assigned
|
–
|
M
|
| |
MetaCyc:
RXN-17472
|
|
|
|
(7R,8S)-8-amino-7-(carboxyamino)nonanoate + ATP <=> dethiobiotin + phosphate + ADP + H+
|
not assigned
|
–
|
M
|
| |
MetaCyc:
RXN1ZN3-10
|
|
|
|
dTTP + (7R,8S)-diaminopelargonic_acid + NaHCO3 <=> dTDP + phosphate + dethiobiotin + Na+ + H2O
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS443946
|
|
|
|
dethiobiotin + Na2S <=> biotin
|
2.8.1.6
biotin synthase
|
–
|
|
| |
BRENDA:
BS388522
|
|
|
|
ITP + 7,8-diaminononanoate + CO2 <=> IDP + phosphate + dethiobiotin
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS651
|
|
|
|
GTP + 7,8-diaminononanoate + CO2 <=> GDP + phosphate + dethiobiotin
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS653
|
|
|
|
CTP + 7,8-diaminononanoate + CO2 <=> CDP + phosphate + dethiobiotin
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS652
|
|
|
|
UTP + 7,8-diaminononanoate + CO2 <=> UDP + phosphate + dethiobiotin
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS650
|
|
|
|
ITP + (7R,8S)-diaminopelargonic_acid + NaHCO3 <=> IDP + phosphate + dethiobiotin + Na+ + H2O
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS443662
|
|
|
|
GTP + (7R,8S)-diaminopelargonic_acid + NaHCO3 <=> GDP + phosphate + dethiobiotin + Na+ + H2O
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS443610
|
|
|
|
CTP + (7R,8S)-diaminopelargonic_acid + NaHCO3 <=> CDP + phosphate + dethiobiotin + Na+ + H2O
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS443406
|
|
|
|
UTP + (7R,8S)-diaminopelargonic_acid + NaHCO3 <=> UDP + phosphate + dethiobiotin + Na+ + H2O
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS443964
|
|
|
|
dethiobiotin + sulfur <=> biotin
|
2.8.1.6
biotin synthase
|
–
|
|
| |
BRENDA:
BS360047
|
|
|
|
ATP + (7R,8S)-diaminopelargonic_acid + NaHCO3 <=> ADP + phosphate + dethiobiotin + Na+ + H2O
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS443084
|
|
|
|
dethiobiotin + sulfur + 2 S-adenosyl-L-methionine <=> biotin + 2 L-methionine + 2 5''-deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
B
|
| |
BRENDA:
BS398860
|
|
|
|
dethiobiotin + sulfur + S-adenosyl-L-methionine <=> 9-Mercaptodethiobiotin + L-methionine + 5''-deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
|
| |
BRENDA:
BS426289
|
|
|
|
dethiobiotin + sodium_selenide <=> selenobiotin
|
2.8.1.6
biotin synthase
|
–
|
|
| |
BRENDA:
BS388521
|
|
|
|
ADP + 7,8-diaminononanoate + CO2 <=> AMP + phosphate + dethiobiotin
|
6.3.3.3
dethiobiotin synthase
|
–
|
|
| |
BRENDA:
BS654
|
|
|
|
ATP + dethiobiotin + CGGGSGGGSGLNDIFEAQKIEWH <=> AMP + diphosphate + desthiobiotinylated_CGGGSGGGSGLNDIFEAQKIEWH
|
6.3.4.15
biotin---[biotin carboxyl-carrier protein] ligase
|
–
|
|
| |
BRENDA:
BS443133
|
|
|
|
ATP + dethiobiotin + CoA <=> AMP + diphosphate + dethiobiotinyl-CoA
|
6.2.1.11
biotin---CoA ligase
|
–
|
|
| |
BRENDA:
BS154
|
|
|
|
N-DL-desthiobiotinyl-p-aminobenzoic_acid + H2O <=> dethiobiotin + 4-Aminobenzoic_acid
|
3.5.1.12
biotinidase
|
–
|
|
| |
BRENDA:
BS116052
|
|
